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More specifically for the sequencing-derived DMRs, a series of values for the argument cutoff (the minimum absolute t statistic) was passed to the function dmrFinder from the Bioconductor package bsseq, after CpG sites were filtered for a minimum coverage of two reads.
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For instance, while the annual mean of temperature has significant eQTLs enrichment under two tail cutoffs, the minimum temperature in winter and the maximum temperature in summer have significant signals over all three tail cutoffs (supplementary table S1, Supplementary Material online).
While pixel size imposes a cutoff on the minimum floe-size detectable, image size has an influence on the statistics of large objects.
By setting a relatively tight cutoff of the minimum similarity of 0.88 in the HCE, clusters containing more than one compound were obtained and labeled as A through F from top to bottom.
Weight loss rates of 0.5 to 2.0 lbs./week are generally recommended in behavioral weight loss interventions [ 18], and this cutoff represents the minimum expected weight loss for a 16-week program.
All experiments were run with Oases version 0.2.01, and Velvet 1.1.06 and the coverage cutoff and the minimum support for connections were set to 3. TransABySS 1.2.0 was run with ABySS 1.2.5 through the first two stages of transABySS (assembly and merging, before mapping to a reference genome is required).
Comparison with the Y. enterocolitica strain 8081 genome sequence [GenBank: AM286415 and AM286416 (plasmid)] [ 12] was performed using BRIG [ 41], SEED [ 42] and the progressive Mauve [ 43] algorithm with default settings and a 1,500 bp cutoff as the minimum LCB length.
To estimate the specificity of our tags and to establish an optimal cutoff for the minimum number of counts a tag should have in order not to be considered artefactual, we performed a series of simulations mapping iteratively randomized sets of our data.
During the past decades much research has aimed at establishing cutoffs representing the minimum amount of change in various HRQOL scores that patients would consider important or beneficial, 14 often referred to as minimum important change (MIC).
The smallest cutoff value is the minimum observed test value minus 1, and the largest cutoff value is the maximum observed test value plus 1.
The cortical distribution of such points of Z-score beyond the individual's threshold was thus known a posteriori, by using the corresponding current density cutoff value as the minimum current to be plotted.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com