Colon became angry when Thurman, who had opposed the funding cutoff, suggested an independent audit of the agency.
Cutoff was controlled as described previously [ 42] and verified the cutoff suggested by the manufacturer.
Fortunately, the most permissive cutoff suggested by the data (3.5 Å) is rather generous.
Because ChIPseek uses HOMER to identify potential motifs, ChIPseek only reports motifs that have p-values smaller than 1e-10, whish is the cutoff suggested by the HOMER website.
For each of the other domains covered by Pfam 27.0, we used the noise cutoff of domain cutoff and sequence cutoff suggested by Pfam 27.0 (Additional file 2: Table S2).
After removal of all genes showing zero expression, only the top 70percentt of the normalized data were taken into account for most analyses, including detection of differentially expressed genes, similar to the cutoff suggested by [ 75].
Ninety-five of 3,433 WN virus peptides scored above a predetermined cutoff, suggesting that these would be likely to bind to HLA B*07 and would also be likely candidate CTL epitopes.
The change in expression of a majority of these E2F target genes fell below our 2-fold cutoff, suggesting that these genes themselves are not likely direct targets of Arx; however, the expression of the E2F family members was not altered greater than our cutoff in the conditional Arx mutant.
Figure 6 presents the observed FDR and power using uncorrected, BH corrected, and BY corrected P-values for the simulations based on model G. Figure 6, top, shows that, except for the AIC-based nonparametric CMST, the observed FDRs were considerably lower than the P-value cutoff, suggesting that multiple testing adjustment is not necessary for the CMST tests.
