When we used a 2-fold cutoff in addition to an FDR-corrected P < 0.05 cutoff, the number of genes differentially expressed in head and testis between Y M and III M males goes down to 373 and 558, respectively.
The cutoff, in addition to the fact that many very recent duplicates were not included on the microarray and could not be analyzed, made the distribution of Ks values in recent and single duplication events highly similar (Additional file 8a, b).
In particular, we still employ the transform level J=7 and cutoff τ=2, in addition to keeping the first PC-based detail coefficient matrix reconstruction in DCA for the sake of consistence.
The finding that scores on the ORTO-11-Hu were significantly associated with ON-related behaviors in our sample supports the previous opinion of the inadequacy of the cutoff point in addition to the construct validity of the instrument.
However, by introducing a global Infernal E-value cutoff of 1e-3 in addition to the gathering score cutoff, we were able to cut the number of false positives in the shuffled data down to just one low confident hit and no high confident hits.
We note that the lower and upper cutoffs have to be reported in addition to the mass fractal dimension value.
In addition to the cutoff from the European Union, which gave about $600 million last year, and from the United States, Israel has stopped turning over the roughly $50 million a month it collected in taxes on behalf of the Palestinians, and Israeli banks are severing ties with the Authority.
In addition to determining cutoff values, sensitivities and specificities, multiple comparison tests were performed to calculate the degree of agreement among the ELISA, FMIA and IFA tests.
First, on logistic regression model to test the added value of non-memory measures and biomarkers, in addition to a cutoff of < −1 SD on two memory tests (B = 2.55, SE = 0.33, p <0.001), MMSE was a significant predictor of future AD (B = −0.34, SE = 0.08, p <0.001).
Altogether, this model accounted for 83.4%% of the variance in risk of probable AD (Table 1).> In the second model, in addition to a cutoff of < −1.5 SD on one memory test (B = 3.09, SE = 0.54, p <0.001), significant predictors of probable AD were MMSE (B = −0.32, SE = 0.07, p <0.001) and the Trails B/A ratio in the non-memory cognitive measures block (B = 0.27, SE = 0.13, p = 0.033).
This model accounted for 82.3%% of the variance in risk of probable AD (Table 2).> In the third model, in addition to a cutoff of < −2 SD on one memory test (B = 2.04, SE = 0.28, p <0.001), significant predictors of probable AD were MMSE (B = −0.40, SE = 0.08, p <0.001) and the Trails B/A ratio in the non-memory cognitive measures block (B = 0.31, SE = 0.13, p = 0.017).
