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The most significant predictor was found for the logistic regression NTCP model with V16 Gy as the cutoff dose for group 0 and V40 Gy for group 1, respectively.
The most significant dose-volume predictive factor for the logistic regression NTCP model was determined by the LASSO with V16 Gy as the cutoff dose for group 0 and V40 Gy for group 1, respectively.
Our finding showed the most significant predictor for the logistic NTCP model with V16 Gy as the cutoff dose for patients without prior abdominal surgery and V40 Gy for patients with prior abdominal surgery.
The most significant predictor was found for the logistic NTCP model with V16 Gy as the cutoff dose for group 0 and V40 Gy for group 1. Logistic regression NTCP model parameters were TV10 ≈ 290 cc for V16 Gy and TV10 ≈ 75 cc for V40 Gy, respectively.
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When RA patients receiving leflunomide plus methotrexate were classified into two groups according to the optimal cutoff cumulative dose of leflunomide (19,170 mg), abnormal LSM values were more frequently identified in patients with high cumulative dose of leflunomide (odds ratio, 12.750; P<0.001).
5percentt as the cutoff for dose reduction and 10 days as the cutoff for the delay were defined because such were minimal modifications observed in our study.
The storm-time effect of solar proton geomagnetic cutoff decreases on dose variations is estimated.
Further, when we stratified our study population into two groups based on a previously proposed cutoff MTX cumulative dose of 4,000 mg [ 13], the proportion of patients with abnormal LSM values was equivalent between the groups (P = 0.572).
We partitioned the TTField-treated cohort using a dexamethasone dose cutoff from 0.0 to 37.0 mg per day, plotted the respective median OS of the groups at ⩽cutoff or >cutoff vs successive dexamethasone dosages, and fitted the data with the best curves using the nonparametric Loess local polynomial regression (Cleveland, 1979; Cleveland and Loader, 1996; Shipley and Hunt, 1996).
The high concentration cutoff in the dose-response curve reflects a complete loss of sensitivity at high, but non-physiological, RIF-1 concentrations.
Also 50 mg/kg/day is considered to be the cutoff for low-dose effect of genistein based on the weight-of-evidence (WoE) evaluation of in vivo studies [ 25].
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