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The method is intended for applications using cutoff calculations, such as evaluating particle penetration of spatial boundaries, calculating magnetospheric transmissions for low-orbital spacecrafts flights and interpreting the results of orbital experiments.
For cutoff calculations, the citrulline-specific signal was used (difference in fluorescence intensity between the citrullinated peptide and the arginine-containing peptide).
Microsoft Excel 2007 spreadsheets were used to collect the raw data and perform OD cutoff calculations while statistical analyses were run in SPSS (15.0).
Because only 3 of the tested environments had SNPs meeting this condition, associations were considered as significant if –log10(p) > 4, as suggestive if –log10(p) > 3 and as supporting if –log10(p) > 2, based on FDR cutoff calculations performed with the R package fdrtool, proposing a cutoff of –log10(p) > 2.
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For datasets obtained using different platforms, the best cutoff calculation was performed to obtain cutoff values for each risk group.
This paper is a review of the progress made in geomagnetic cutoff rigidity calculations over the past 50 years.
The procedure of the Lane method for cutoff grade calculation is complicated and time-consuming.
In the proposed method, wavelet theory is used to extract noise information which enhances the accuracy of cutoff frequency calculation and improves filtering performance.
This is in accord with our observations; Fig. 4 shows that the optimal cutoff for calculation of HGI lies between 6.0 and 8.0 mmol/l.
The cutoff for calculation of sensitivity and specificity is set to select the top pairs with the same number of the test set.
Statistical verification of our choice of cutoff by calculation of Bonferroni corrected p-values cannot be applied with data sets of this size, since cutoffs of as little as 0.2 can easily become statistically highly significant, while biological relevance at this low cutoff would be unlikely [ 28].
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com