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Moreover we observed that administration of a FbnE-enriched scaffold together with EPCs into mouse cutaneous wounds increases wound vascularization and consequent healing [ 54].
Indeed, it has been reported that topical application of NGF to cutaneous wounds hastened wound healing in normal and healing-impaired diabetic mice [ 7, 21].
Treatment of cutaneous wounds with MSCs accelerates wound healing kinetics and increases epithelialization and angiogenesis [ 64- 66].
Recently, autologous ADSCs were found to accelerate wound healing in human cutaneous wounds.
FMOD reduced scar formation and increased wound tensile strength in adult rat cutaneous wounds.
FMOD reduced scar formation and increased wound tensile strength in adult Yorkshire pig cutaneous wounds.
Bilateral dorsal cutaneous wounds were made on 8-week-old female Balb/c mice.
Cutaneous wounds, acquired from surgery or trauma, can cause pathologic scarring with significant functional and psychological sequelae.
Sun, B. K., Siprashvili, Z. & Khavari, P. A. Advances in skin grafting and treatment of cutaneous wounds.
An extended epidermal response heals cutaneous wounds in the absence of a hair follicle stem cell contribution.
Early in utero, but not in postnatal life, cutaneous wounds undergo regeneration and heal without formation of a scar.
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