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We concluded that the endogenous matrix metalloproteinase-2, -9, -14 and their endogenous inhibitors might be involved in skin development and in maintenance of cutaneous structure and function.
The newly developed ultrasound technology could help identify several other complementary parameters of the skin (vascular structures, cutaneous elasticity), allowing a more thorough characterization of the cutaneous structure.
7, 8 Several changes of the cutaneous structure after topical prednisone therapy in children, or anti-aging natural supplement therapies in adults were ultrasonographically successfully assessed.
6 High-frequency ultrasound allows an objective assessment of the cutaneous structure: the thickness of the epidermis and dermis as well as the dermal density, which are useful parameters for the quantification of the cutaneous regeneration process.
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However, it does raise the interesting question of whether some early autoimmune events might take place in cutaneous structures.
Upregulation of skin-specific autoantibodies may indicate that early events in the break of tolerance take place in cutaneous structures.
It has long been accepted that facial aging is the result of deterioration and descent of cutaneous structures due to downward gravitational pull, hormonal changes, photo-damage and smoking, among others.
The challenge of repairing a skin defect entails restoration of the cutaneous anatomical structures and functions.
According to our observations, there is a direct relationship between the genetically determined cutaneous phototype, the structure and repartition of echogenic proteins (collagen, elastin) and the different response to anti-aging therapies.
These observations constrain models of receptive field size and structure among cutaneous sensory neurons, and they raise intriguing questions regarding the cellular and developmental mechanisms responsible for this morphological diversity.
Amputations damage cutaneous, nervous, musculoskeletal, and vascular structures, and alter lymphatic drainage.
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