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It is our conviction that the approach to statistically fit a function of the DL decrease over the whole range of interval accretion applied gives a more precise estimate of the before and after multiple-look effects than does the stepwise (interval by interval) statistical cut off procedure by Panissal-Vieu and Drake.
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Search procedures such as PSI-BLAST and RPS-BLAST have been used at stringent E-value cut off of 0.0001.
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