In this work, we considered a recently proposed holographic cosmological model with IR cut-off given by the modified Ricci radius dubbed as 'modified holographic Ricci dark energy' [32].
In this work, we consider a recently proposed holographic cosmological model with IR cut-off given by the modified Ricci radius so that L−2 is a combination of H2 and H ̇ Open image in new window (with H and H ̇ Open image in new window being, respectively, the Hubble parameter and its first derivative with respect to the cosmic time t) [32, 33, 34].
After subtracting the background, the difference of 1.7-fold in the signal intensity between the experimental conditions used (promastigote vs. amastigote RNA) for a given gene was chosen as the cut-off given that the p value confidence was more than 95% under those conditions.
The statistic was calculated in a linear model framework provided by the library limma, which is part of the BioConductor suite of libraries for the statistical programming language R. The p-value cut-off, given above, for significance was established by inspecting the distribution of p-values associated with the control probes on the microarray.
This study has the ability to assess the role of baseline exposures to SHS in the estimate of cut-offs, given the detailed information collected on SHS exposure and its elevated prevalence.
One of the main strengths of this study was the possibility of assessing the role of baseline exposures to SHS in the estimate of cut-offs, given the detailed information collected on SHS exposure and its elevated prevalence.
The association of the model with nephropathy using the equal error cut-off gave similar results (data not shown).
We found that larger or smaller inter-HRE distance cut-offs gave worse correspondence with genome-wide ChIP-chip measurements of GR occupancy.
Lower Z-score cut-offs give better detection sensitivity to the E coli definitions (Table 9), but the lowest value we used was Z = 0.4, as we want to build our networks using observable changes in gene-expression.
However the lack of resolution was not caused by this stringent cutoff, as a 60% cut-off gave essentially the same results, with only two clades supported by more than half of the trees (Table 4).
