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Custom tissue compensators provide dosimetric advantages for treating superficial or complex anatomy, but currently available fabrication technology is expensive or impractical for most clinical operations and yields compensators that are difficult for patients to tolerate.
For this purpose, a custom tissue array containing a set of paraffin-embedded samples of different tumor and normal tissues was created.
The mRNA levels were measured by quantitative real-time PCR and hybridization of a tumor tissue cDNA array; and the protein levels and distribution by immunostaining of a custom tissue array containing a set of paraffin-embedded samples of different tumor and normal tissues followed by statistical analysis.
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To evaluate the results and complications of hyperopic laser in situ keratomileusis (LASIK) with a low-energy femtosecond laser and non-custom tissue-saving ablation profile.
Tissue engineering is a fascinating area of development, and CAD and RP approaches are being actively developed in many research centers to facilitate the direct manufacture of custom fitting tissue scaffolds or even living tissue constructs.
The ability to deliver sustained-release, biologically active growth factors through custom designed tissue engineering scaffolds at sites of tissue regeneration offers great therapeutic opportunity.
Custom made tissue microarrays (T12 412) using oral cancer specimens contained above formalin-fixed, paraffin embedded tissues.
Design of a custom gridded tissue culture dish facilitated single-cell comparisons between cell mechanics and other differentiation biomarkers by enabling sequential measurement of cell mechanics and protein biomarker expression at the single cell level.
Bioprinting is an advanced manufacturing platform based on conventional 3D printing that enables the predefined deposition of biomaterials, living cells, and growth factors using computer-aided design (CAD) to fabricate custom designed tissue constructs by layer-by-layer printing process with a high degree of flexibility and repeatability (Murphy and Atala 2014a) (Ng et al. 2016a).
While remaining hydrated the femur-MCL-tibia complex was placed into a custom designed tissue bath system with special structures to hold the femoral and tibial bone sections of the sample along the longitudinal axis of the MCL where all fibers appear to load simultaneously (~70° flexion).
Provisional restorations are indicated in esthetic zones, for the contouring of the gingiva, to achieve an acceptable emergence profile, to have custom-guided tissue healing, and to induce appropriate soft-tissue topography.
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