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During the XVIth century, the jurists of the "French school of law" showed that the law is tied up with historical determinations.[42] In chapter I,23, 'On custom', Montaigne seems to extrapolate on this idea : our opinions and conducts being everywhere the product of custom, references to universal "reason", "truth", or "justice" are to be dismissed as illusions.
The usage of custom references sequences is also supported.
As outlined in Figure 1, unsupported or custom references can be defined and their associations plotted and exported.
References and index files for the aligners can be automatically downloaded from Ensembl (Hubbard et al., 2009) and created upon request, or manually provided in a local directory for alignment to custom references.
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However, current BCG reference layer (BRL) methods either use a customized EEG cap composed of electrode pairs, or need to construct the custom reference layer through additional model-building experiments for each EEG-fMRI experiment.
The additional but necessary step of setting a custom reference system to calculate tip and torque angles may account for the higher degree of variation of the angular measures when compared to the linear measures.
We built a custom reference sequence database that covers all pathways and enzymes represented in the MetaCyc [45] pathway database by combining the protein sequences that are distributed with MetaCyc (including sequences for which only cross references to external databases were provided) with EC-number associated sequences from the SwissProt Enzyme database [46].
In these situations, the citation is to a custom reference.
We first construct a sample-specific custom reference genome in a two-step process.
The GM12878 custom reference was created by further modifying this initial custom reference by replacing non-reference homozygous variants with the new allele, based on information from either the full genotype or partial genotype.
Intuitively, our approach corresponds to imputing each study haplotype from a "custom" reference panel containing close genealogical neighbors.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com