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The aim of this study was to systematically review the content validity and measurement properties of all physical function (PF) scales which are currently validated for use with patients with rheumatoid arthritis (RA).
Several biomarkers, related to the biology of fibrogenesis are currently validated for their use as diagnostic and prognostic indicators of disease progression in different chronic liver diseases.
The protocols currently validated for use in routine diagnosis are IHC for identifying HER2 protein overexpression, and FISH or CISH for determining HER2 gene amplification.
None of the PROMs identified are currently validated for use as predictive tools for the future hip OA risk in active people.
Hybrid capture II (HC2) and most other HPV assays currently validated for use in primary cervical cancer screening may not be able to fulfill this optimal purpose 10.
However, most sequencing platforms currently validated for clinical use, such as Sanger sequencing, pyrosequencing, and primer extension coupled with mass spectroscopy, are limited in their ability to assess multiple markers simultaneously using small amounts of DNA.
Similar(53)
LPAs are currently validated only for use directly from smear-positive specimens, although reasonable performance in a small sample of smear-negative specimens was demonstrated by Barnard and colleagues [ 9].
19 Thus, the Lille model represents the best currently validated dynamic criterion for the assessment of mortality in AH, and the only one linked to specific stopping rules for corticosteroid management: in poor responders (Lille >0.45) discontinuation of corticosteroids is recommended, 19 particularly when Lille >0.56 (i.e. considered null responders).
Despite none of the currently validated tracers is ideal for peripheral CB1R imaging, 18F-MK-9470 seems suited for imaging CB1R in PCa as previous reports demonstrated a high selectivity and affinity of 18F-MK-9470 for CB1R [20].
Despite the promising prognostic value of circulating tumor cells, no biomarker has been currently validated as a surrogate for overall survival in CRPC patients.
Thermodilution monitoring cannot be used because of recirculation phenomena [ 31], and preload reserve haemodynamic indices are not currently validated in this setting for the reasons described above.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com