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However, one of the main issues of currently used indicators is the lack of case-mix correction and improvement possibilities.
The theory-based framework encompasses currently used indicators for visual assessment based on four different data sources: land cover data, aerial photographs, landscape photographs and field observations.
To illustrate the potential application of the framework, a set of currently used indicators was selected, whereupon these indicators were structured and evaluated within the framework.
This issue is certainly of more translational relevance, and may add significant prognostic value to the currently used indicators for outcome prediction in breast cancer progression.
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In a preliminary step, 120 currently used energy indicators were examined to assess their suitability as an energy benchmark.
High expression of all of them was associated with a better outcome (Fig 6D), and interestingly, a multivariate analysis revealed that all of them, except CD6, seem to have an independent prognostic value to currently used clinical indicators (Fig 6E; Table SXXVIII of Supporting Information).
The extent to which EBF is reaching 6 months should be the indicator on center stage instead of the currently used prevalence indicator.
The currently used impact indicator in Flanders, the Significance Score, was compared with the Aggregate Deposition Score, an alternative that is a better reflection of the total damage caused by airborne ammonia emissions in nearby Natura 2000 sites.
The currently used prevalence indicator has some advantages and has a legitimate role.
For comparison, the accuracy of a currently used prognostic indicator of future ALS progression rate, the time from first symptom to first examination, was evaluated using the same 54 patients.
FoxP3 and Gata3 expressions were more accurate at reflecting progression rates than the time from first symptom to first exam, a currently used prognostic indicator of future ALS progression rates (Czaplinski et al, 2006; Kollewe et al, 2008).
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com