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The literature has currently not established the direction of causality; however, it is highly likely that the relationship is bi-directional.
Whether vitamin D has a causal association with reduced risk of T2D is currently not established, but epidemiologic evidence suggests an inverse association (24).
While the Sicily Statement [ 7] has recommended that instruments cover the five step process model, it is currently not established which core competencies should be included in each of the EBP steps, and whether these competencies are different between professions.
However, it is currently not established whether NDR1/2 kinases can also regulate F-actin remodelling, although a NDR2/actin complex has been reported nearly a decade ago [ 151].
As this threshold is decreased during pregnancy, the clinical value of using 1,5-AG to evaluate glycaemic control in pregnant women with type 1 is currently not established.
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The utility and safety of endoscopic biliary orifice balloon dilation (EBD) for bile duct stone removal (with use of large-diameter balloons) after biliary endoscopic sphincterotomy (BES) is currently not well established.
The practical significance of these inferences depends on the duration and intensity of the AIB, which is currently not well established.
Copy number variations (CNVs) have been well documented to contribute significantly to some genetic disorders; however their frequency is currently not well established in many rare conditions.
This assay will allow deletion/duplication analysis for disorders known to be caused by deletions or duplications within a single gene as well as for disorders for which the frequency of gene deletions/duplications is currently not well established.
The mechanism by which CDH1 expression is lost is currently not well established.
However, optimal dosage and scheduling in infants and children is currently not well established.
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CEO of Professional Science Editing for Scientists @ prosciediting.com