Further investigations are needed to assess the risk of nano-silica in other environmental compartments, which is currently not possible due to a lack of ecotoxicological data.
Furthermore, a validation of the results of the predicted environmental concentration (PEC) calculation is currently not possible due to the lack of appropriate techniques and devices in order to determine environmental concentrations.
As demonstrated in a recent review by Land et al. [55], a generalized prediction of temporal trends in environmental concentrations of short-chain PFAAs is currently not feasible due to limited monitoring data and insignificant time trends shown in most of the studies.
A GPR126 homologue is also present in the amphibian Xenopus tropicalis, but although synteny also appears to be conserved a comprehensive annotation is currently not possible due to the fragmentation of sequence contigs.
Moreover, the ability to cheaply and rapidly sequence material from different habitats not only increases the efficiency of biomonitoring as a technique, but it expands the scope of monitoring programs, by extension into habitats and biota groups which are currently not studied due to poor taxonomic knowledge or technical competency.
In C. parvum, experimental analysis of promoters and gene expression, including microarrays, is currently not possible due to the aforementioned experimental limitations.
Our experiment was not designed to investigate the state of pulmonary epithelial cells in infants prior to RSV exposure, and such an experiment is currently not feasible due to ethical and practical issues.
In the case of oxidative stress related to septic shock, administration of more than 700 μg/day selenium is currently not recommended due to the pro-oxidative effect of selonocompounds [ 23, 29- 31].
While the direct study of randomly selected patients with a history of CABG is currently not feasible due to lack of indication for CTA, the present investigation represents an adequate pilot study.
The KRT23 expression was monitored by quantitative RT-PCR, because to the best of our knowledge the direct monitoring of the expression on the protein level is currently not possible due to the lack of a specific antibody.
