Sentence examples for currently designed to target from inspiring English sources
We describe here some of the latest knowledge accumulated on this pathway and the pending questions, present the most convincing findings about its role in cancer, and review the most promising strategies currently designed to target its components.
Currently, inhibitors are primarily designed to target the ATP binding pocket, the region of greatest conservation amongst kinases.
Currently, most cancer drugs are designed to target the general mechanisms of cell division, which may not directly address the specific molecular mechanisms that drive the development of the type of cancer it aims to treat.
Because currently available drugs are not specifically designed to target ER stress or ER dysfunction, we should create novel small molecules to control ER homeostasis in Wolfram syndrome in addition to using FDA-approved drugs (Fig. 2).
We also discuss the creation of multiple other myeloma agents currently in phase I/II testing and designed to target specific pathways in myeloma physiology.
Currently, two small molecule inhibitors have been designed to target SGK1, suggesting that inhibitors for other members of this kinase family may also be in development.
Naturally occurring and synthetic drugs designed to target the UPS are currently used for hematological cancers, including lymphoma.
Furthermore, the WHO Nutrition-Friendly School Initiative [ 21] — specifically designed to target DBM through health promotion — is currently being tested in pilot schools in Ouagadougou and Cotonou.
Four different antibody molecules designed to target the CD47-SIRPα interaction in malignancy are currently being studied in clinical trials: Hu5F9-G4, CC-90002, TTI-621, and ALX-148.
There are currently vast arrays of PI3K-targeted molecular inhibitors in production, some of which are pan inhibitors designed to target all isoforms, and others which are isoform specific.
Because equine influenza is caused currently by EIV of the H3H8 subtype, the RT-LAMP primer set was designed to target the hemagglutinin gene of this subtype.
