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In particular their optical properties that can be easily tuned by either variation of particle size and composition and/or subsequent surface modification are currently comprehensively studied.
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Based on the assumption that PrPSc corresponds to (or at least is part of) the pathogenic entity, various approaches aiming at reducing PrPSc or PrPC levels for the development of prion disease therapies are currently explored (comprehensively reviewed in [1]).
It is currently difficult to comprehensively understand this diversity, although a clue may be that the AIB tends to have a short duration when it intensifies rapidly (Nishimura et al. 2016).
No methods are currently available to comprehensively characterize either the variety of activities or their relative frequencies.
[ 31- 34] Genome-wide scanning approaches have been shown to be powerful for discovering common variants that influence complex disease phenotypes; however, these approaches currently fail to comprehensively survey coding variation, particularly uncommon alleles in non-European populations.
Note that it is not currently possible to comprehensively apply this filtering step to NOTCH1 and RELA gold standards because the transcription factors are not well known in human cells.
Wastewater comprises significant amounts of chemical energy primarily in the form of organic molecules (in particular lipids), which are currently not being recovered comprehensively.
Programmed necrosis induced by tumor necrosis factor (TNF -receptor 1 (TNF -receptorntly represents the most comprehensively studied system.
Although the guidelines list suggestions for improved reporting, there is currently no requirement to comprehensively and uniformly identify and report all details of research in a study protocol.
This technology is already being used to study issues such as coral response to climate change [ 47– 49] and disease [ 50], and is the best currently available method to comprehensively study total transcriptomic variation.
Currently available questionnaires do not comprehensively assess the range of problems, nor impact on quality of life associated with proctitis.
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