They would have to be paid on the teachers' pay scale, with benefits, which is more expensive than the current substitute teacher pay structure.
The current substitute is more likely to be the winter truffle, Tuber brumale, which sells for about 900 euros a kilogram.
Despite the advancements in technology current valve substitutes continue to have significant limitations with regards to thrombogenicity, durability, and inability to grow or remodel.
Bony defects have been three-dimensionally (3D) created in many clinical circumstances; however, many defects cannot be reconstructed because most of the current bony substitutes cannot provide the necessary exact 3D structure.
As it is HA that possesses high biocompatibility with human organism, many of the current biomaterial substitutes for bone tissue are various composites on the basis of HA and/or other calcium phosphate materials such as β-tricalciumphosphate (β-TCP), β-Ca3(PO4)2, calcium pyrophosphate (Ca2P2O7), tetracalciumphosphate (TTCP), and Ca4(PO4)2O).
Current vitreous substitutes are primarily categorized on the basis of the duration of the tamponade effect, either short term, such as with various gases, or permanent, such as with silicone oil (polydimethylsiloxane, PDMS) and HSO.
Current bone substitute approaches are still limited in effectiveness and to date no adequate bone substitute material has been developed for routine clinical application.
They project aggression with artifice, enacting the line in their then current hit, "Substitute" – "The simple things you see are all complicated".
Current renal replacement therapies substitute for the small solute clearance function but they do not replace the transport, metabolic, and endocrinologic functions of the tubular cells, which renders them partially substitutive.
Newer gel-, cellulose-, and mineral oil-based formulations have been designed to overcome the disadvantages of current aqueous tear substitutes by offering prolonged retention times.
