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In any case our results in Figure 6 strongly suggest that ongoing selective processes other than paralogy reduction by either DNA elimination or gene-by-gene inactivation are responsible for the current fractionation bias in the descendants of the old events.
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A new counter-current process has been developed for large-scale enantiomer separations, based on a combination of enantioselective complexation in solution, counter-current fractionation and electrodialysis.
The 10-step counter current membrane fractionation revealed that the ER marker choline phosphotransferase was active in fractions enriched in plasma membrane (Fig. 1A), indicating presence also of ER in these fractions.
The US-based donor population for this preparation was, however, fully qualified and consistent with the stringent standards required for current plasma fractionation, a situation entirely different from the biosafety challenges associated with bringing reconvalescent plasma from the current Ebola-endemic regions into fractionation facilities licensed according to good manufacturing practices.
SCFs are used for batch extractions of solids, for multi-stage counter-current separation (fractionation) of liquids, and for adsorptive and chromatographic separations.
2) Figure 1 and 2 do not follow the text presentation and in my opinion would benefit the manuscript and help the reader if Figure 1 was made in sequence of panels: Figure1D, 1A, 1B, Figure 2, 1E Figure 2 should then be the fractionation (current Figure 1 C) and Figure 1 figure supplement 2. The text in the results sections should be changed to reflect this.
Current stable-isotope-fractionation-based techniques focus on the identification of dominant biodegradation pathways under constant environmental conditions.
In the current study, we show that fractionation of DNA is highly essential for reliable detection of LOH in serum samples of ovarian cancer patients.
The principal manufacturing process in all current Ig preparations is cold ethanol fractionation with product-specific additional processes for manufacturing.
The current mathematical models applied for dose fractionation allow us to predict the rate of late neurological side effects but are not applicable for a dose over 8 Gy.
The current study provides important insights into dye/salt fractionation by loose NF membranes for digital ink-jet printing.
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