Current forensic biochemistry analytical technologies permit a significant amount of individual-specific genetic information to be obtained from a biological stain found at a crime scene [1].
Previous estimates of the thermodynamic efficiency of this vital process have ranged from Lehninger's original back-of-the-envelope calculation of 38% to the often quoted value of 55 60% in current textbooks of biochemistry, to high values of 90% from recent information theoretic considerations, and reports of realizations of close to ideal 100% efficiencies by single molecule experiments.
Also encouraging, Dr. Bernard said, is that the current understanding of the biochemistry of sepsis should soon result in the development of other specific therapies.
This Perspective summarizes the current understanding of nitrification biochemistry and highlights exciting opportunities for future research.
This paper reviews the current knowledge of the biochemistry behind yeast ester synthesis and discusses the different factors that allow ester formation to be controlled during brewery fermentation.
This review highlights our current understanding of the biochemistry and molecular biology involved in these natural arsenic metabolisms, and some successful examples of engineered microbes by harnessing these natural mechanisms for effective remediation.
Here, current views on the biochemistry and genetics of the core isoprenoid metabolism in land plants and in the major algal phyla are compared and some of the most pressing open questions are highlighted.
Current advancements in the biochemistry and structural biology of ABC transporters indicate that these systems operate by a mechanism in which binding sites in the MDs for transport substrate(s) are alternately exposed to the inside and outside surface of the membrane in response to the ATP-driven dimerization of NBDs and their dissociation following ATP hydrolysis (for reviews, see Ref. 35, 36).
In this review article, we give a concise account of our current knowledge on the biochemistry and regulation of CHIP.
While the specificity of many HATs is beginning to be determined (6, 7), the current knowledge of HDAC biochemistry is limited by a lack of activity assays that are convenient and compatible with peptide substrates that suitably mimic the endogenous histone substrates.
