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But the likely cure observed in the Mississippi case has changed that risk-benefit ratio, presenting researchers with critical questions.
Since the microbiological assay seems to measure the total microbiological action, it was considered the more appropriate to measure the in vivo drug concentrations effectiveness, with the goal of correlating with the clinical and bacteriological cure observed on the clinical practice [ 15].
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The epoxy resin was cured by heating with bisphenols in the presence of a catalytic amount of imidazole, with more rapid curing observed for more soluble bisphenols.
So, the post-cure observed can be ignored.
While tumour regrowth after PDT, when it occurred, commenced at the same time in sgp130 and control groups, and proceeded at the same rate, sgp130 reduced the tumour cures observed with PDT alone.
At 6 months after the end of treatment, paromomycin monotherapy provided only a 63.8% average cure rate with very low cure rates observed in 2 Sudan centers (14.3% and 46.7%).
The PCR-corrected cure rates observed for DHA/PQP in this study were in line with the day-63 PCR-corrected cure rates noted in a previous study conducted in Thailand [32], day-42 rates observed in Myanmar (Burma) [11] and Laos [36] and day-28 cure rates observed in Cambodia [8].
A large decrease in fluorescence intensity at 75 and 95 °C cure was observed.
Contrary to major advances in cure rates observed for almost all childhood cancers, progress in reducing brain tumour survival rates remains very limited.
Finally, all the experimental results have been elucidated in light of the formation of thickening-induced microdomains of aggregates for polyester chain segments prior to cure, as observed by SEM micrographs, and the associated reduction of reactivity for styrene and, especially, polyester CC bonds in these microdomains during the cure.
This difference is most likely related to the difference in cure rate observed between the two treatment arms.
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