Sentence examples for cumulatively fulfilled from inspiring English sources
Restricting the analyses to patients who cumulatively fulfilled the 1987 ACR criteria for RA resulted in similar findings (see online supplementary file tables S1 and S2).
During 342 916 person-years of follow-up, 184 participants (128 (69.6%) women) developed incident IP, of which 138 cumulatively fulfilled criteria for RA; 57.6% and 35.9% were, respectively, RF and ACPA positive (60.4% seropositive).
At 15 years the mean (SD) age of these 421 patients was 62 (13) years and mean disease duration since symptom onset was 16.0 (1.1) years; 68% were female (table 1) and 79.3% cumulatively fulfilled the 1987 ACR criteria for RA.
A Cox proportional hazard model was developed, and a score assigned to each risk factor to calculate the odds of developing IP. 25 455 EPIC participants were followed for a median (IQR) of 14.2 (15.3, 15.3) years; 184 developed incident IP (138 cumulatively fulfilled criteria for RA; 107 were seropositive).
When restricting the univariate analyses to patients who fulfilled the 1987 ACR criteria for RA cumulatively during follow-up (n=378 in cohort 1 and n=340 in cohort 2), ACPA positivity remained the strongest predictor in both cohorts (table 3).
Subsequently, univariate regression analyses were restricted to patients who fulfilled the 1987 American College of Rheumatology (ACR) criteria for RA cumulatively at any of the follow-up visits.
The 313 (49%) subjects fulfilled 1987 ACR criteria for RA at baseline and 463 (72%) fulfilled them cumulatively over the first 5 years of follow-up.
