It reflects on the quality of life of subjects with painful polyneuropathy as lower value of cumulative parameter MCS, as well as higher level of depression according to BDI scale.
Additionally, an extra process to ensure robustness is (c) robust cumulative motion parameters.
Subgrouped angiographically, the median (interquartile range) for cumulative ST parameters with patent (n = 8) versus occluded (n = 14) arteries were, respectively--time to 50% recovery, 1.57 (1.70, 1.70) versus 0.17 (-0.32, 0.32) hours; number of reelevation/recovery events, 1.5 (1, 3) versus 3 (1, 3); and patent physiology index, 52 (47, 59) versus 50 (5, 73).
Cumulative product parameters were defined as the sum of the values across the 3 treatment doses.
The correlation between OS and key cumulative product parameters was examined using a Cox regression model, with and without adjustment for baseline PSA and LDH [ 14– 16, 20, 21].
For a graphical depiction of these correlations, Kaplan Meier curves were generated for sipuleucel-T subjects with cumulative product parameters greater than versus less than or equal to the median value (Fig. 5a c).
The score scatter plot showed good separation of CRC cases and controls with cumulative statistical parameters R(X) = 0.699; R(Y) = 0.996; Q = 0.922 (Additional file 3: Figure S1).
This NLDA model is formulated based on energy principles coupled with a cumulative damage parameter that accounts for the progressive damage accumulation dictated by the path of the load history without any requirement for counting of cycles as have been done in current practice.
We detected the standard C14 hep Zr(Cr,Fe 2 precipitates (the stable second phase in Zircaloy-4) in the bulk material at a cumulative annealing parameter as low as 10-20 h, and we followed the kinetics of precipitation and growth as a function of the cumulative annealing parameter (CAP) in the range 10-22 (quench) to 10-16 h.
