With the given study design, the measure of association from this analysis is interpreted as the relative risk of islet autoimmunity per increase in cumulative number of enterovirus RNA positive samples, with a corresponding 95% CI.
We also analyzed the data according to a formal nested case-control study design using conditional logistic regression (accounting for the matched design with a fixed intercept for each matching group), modeling the cumulative number of enterovirus RNA positive fecal samples before seroconversion (grouped as 0, 1, 2, or ≥3) as the exposure variable.
For example, PTPN13 was examined by both groups but no cMNR mutations were observed in a cumulative number of 69 MSI-H CRC samples ([ 43] and data presented here).
Pairs of control single dose infected animals were administered with a single dose of iL3s on day 0 p.i. either half, equal to or double (Single 2.5, 5 and 10, respectively) the appropriate cumulative number of larvae that the contemporaneously sampled trickle infection animals had received.
The remaining facilities were selected in the same manner until the cumulative number of residents met the estimated sample size required (n = 20 facilities, 10 hostels – low level care and 10 nursing homes – high level care).
To test whether the analyzed sample set is large enough to properly reflect mtDNA variability of contemporary European wolves, we estimated the total number of wolf haplotypes that can be expected in Europe, using the method of rarefaction curve [ 33] that plots the cumulative number of haplotypes found with increasing sample size (for details, see Additional file 1).
In the largest program, we randomly selected health centers sequentially until the cumulative number of CHWs reached the target sample size; all CHWs reporting to those health centers were invited to participate, along with all CHWs in the other 2 smaller programs.
For the 318 C. difficile-negative patients, the cumulative number of days in hospital (within 3 months of sample collection) was 11.7 days.
Species accumulation curves generated from the cumulative number of ribotypes against a measure of the sampling effort indicated that asymptote was likely achieved in S. pistillata (Figure 3E) thus further sampling effort would be unlikely to detect any new ribotypes.
The cumulative number of cases from all influenza B virus positive samples for each of these years (B ).
