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However, fluoride gels in combination with laser showed some cumulative efficacy [ 23].
Nevertheless, 3-year cumulative efficacy rates for the Vi vaccine and the H-P vaccine are estimated to be 30 70 % and 51 77 %, respectively [ 7, 10].
Figure 2 shows the cumulative efficacy of VCIV in preventing CCII from the week ending 24 January to the week ending 9 May 2009.
Combination targeting of Dll4/Notch and Ephrin-B2/EphB4 has potential for clinical investigation, providing cumulative efficacy and increased safety over Dll4/Notch inhibition alone.
Data from a randomized double-blind placebo-controlled clinical trial undertaken in healthy young adults in the 2008 2009 influenza season were used to investigate the weekly cumulative efficacy of a Vero cell culture derived influenza vaccine.
This report presents the cumulative efficacy and immunogenicity results for all subjects who were randomised and vaccinated with low-dose quadrivalent HPV vaccine or placebo, through the extension period.
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The cumulative vaccine efficacy estimates and efficacy up to or after 3 months reported here for the Vero-derived vaccine are similar to those determined for the entire study period, where vaccine efficacy was estimated to be 79% for antigenically matched A/H1N1 strains, 78.5% for all matched strains, and 71.5% for all strains, irrespective of antigenic match [ 1].
Cumulative vaccine efficacy (VE) was computed by the formula VE = (1 − RR) × 100, where RR is the ratio of influenza infection risk in the VCIV group compared with the risk in the placebo group.
We utilized area-under-the-curve (AUC) analysis to assess six-month cumulative treatment efficacy of memantine-donepezil combination versus component monotherapies on individual clinical domains and on a composite index.
To illustrate the trade off between cumulative dose and efficacy: cumulative INH dose for regimen 1a is 105 mg/kg/week.
During the 14-day study period, imipenem-loaded ALBCs showed a significantly worse cumulative antibiotic release efficacy compared with the other tested antibiotics (all p < 0.001) (Table II).
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