Your English writing platform
Discover LudwigExact(12)
We used two parameters for these analyses, to take into account not only similarity but also the relative lengths of the aligned sequences: CIP (cumulative identity percentage) and CALP (cumulative alignment length percentage).
Positional analysis revealed that none of the 75 Crepeatseats in this cumulative alignment had more than one hydrophilic substitution at any of the seven core positions.
For example, in the case of the Exportin fragment the cumulative alignment of the five internal repeat segments was "detected" by both HHpred (E-value 4.3) and COACH (score 11.2).
In contrast, the cumulative alignment of the six B56 internal repeats scored very poorly (HHpred E-value 630, COACH score 1.3) and numerous repeats showed violations of the "constraints against hydrophilic substitutions" rule with two or three hydrophilic substitutions at any of the seven core positions.
The third parameter, CALP is the cumulative alignment length percentage.
Defined by a cumulative alignment score, the 5 to 18 concatenated octacosapeptidic (28-meric) LRRs of LGRs present all a predicted α-helix conformation.
Similar(48)
Valuable information may come from an analysis of cumulative repeat alignments.
We recorded the average cumulative numbers of alignments per query that had E-values better than a given threshold value.
Most studies conclude with the prediction that individual and cumulative improvement in component alignment will ultimately lead to better long-term results.
This approach is subject to cumulative error in the alignment similar to cross-correlation; therefore, we avoid this approach.
The RE within a family (conservation across a subfamily) and CRES scores across all columns of this profile MSA were calculated Supplementary Data S2. Figure 1 shows a representative part of this profile alignment with Cumulative Relative Entropy (CRES), Relative Entropy (RE) and conservation scores for each alignment position.
Write better and faster with AI suggestions while staying true to your unique style.
Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com