As a result, these models require cumbersome variable-switch techniques to deal with phase appearance and disappearance.
Assessment of Atg4 activity has been mainly based on an SDS-PAGE-based assay,,,, which can be cumbersome and highly variable with a relatively low detection sensitivity.
It more closely matches the criteria for usefulness than other candidate biomarkers such as C-reactive protein, which is rather a nonspecific marker of acute phase inflammation, and proinflammatory cytokines such as plasma IL-6 levels that are highly variable, cumbersome to measure, and lack specificity for systemic infection.
Kernel machines can be used to implement several learning algorithms but the interpretability of the resultant output representations may be cumbersome, because input variables are only handled implicitly [ 6].
However, Western blotting can be a cumbersome process involving many variables and multiple steps, including gel electrophoresis, membrane transfer, and immunodetection.
Kernel PCA can be used to reduce dimensionality, thereby improving on linear PCA, but the interpretability of the output representations may be cumbersome because the input variables are only handled implicitly.
Downdraft gasification in such a complex system has so many variables and is quite cumbersome to describe.
Instead of embarking in a cumbersome search of these additional regional variables, we adopted a more qualitative approach to identify signatures specific of selection.
To summarize, cluster analysis is a way of grouping cases of data based on the similarity of responses to several variables, and is useful mainly in situations where there are hundreds of people and lots of variables, which would become very cumbersome and almost impossible to interpret.
This might be the reason for Bolzano's cumbersome way of speaking about "the idea Caius considered variable".
However, the estimation of complex item response models is more cumbersome than in confirmatory factor analyses models with continuous variables and often requires larger sample sizes.
