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Validation of targeted gadolinium probes in tissue however has been cumbersome up to now.
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The costumes are cumbersome, weighing up to about 10 kilograms each, or 22 pounds, with the one for the character "Le Patibulaire" among the heaviest.
We have also reorganized departments so they are less hierarchical and cumbersome, splitting up some areas and focusing others, so that all our Energy and Commodities coverage is now centralized, and our deals team is integrated with corporate finance.
Steve Weller, the head of communications services for uSwitch.com, said: "There is no way that slow, cumbersome dial-up connection will have a place in the home of the future, where entertainment will be underpinned by the broadband connection".
Unlike existing wireless lab-on-a-chip devices that have cumbersome set-ups, require high voltages and perform only one microfluidic function, the presented LOF has a compact and flexible structure, works at very low voltage ranges, and can perform several microfluidic operations corresponding to a wirelessly-controlled voltage.
However, most of the existing methods involve toxic metal ions and solvents, have high costs, use corrosive reagents, and have cumbersome work-up procedures.
Alas, technological progress and the dawn of the CD meant the decade was barely complete before the general public started to recognise that audio cassettes were not, in fact, the medium of the future but a cumbersome, chewing-up-prone source of much annoyance.
But Koh pointed out that the cumbersome get-up isn't the hardest part of the job.
However, massive parallel signature sequencing as well as serial analysis of gene expression require a relatively cumbersome set-up and additional sequence information is required to identify the corresponding transcript.
However, a considerable disadvantage of this method is the somewhat cumbersome work-up of the aqueous reaction mixture in order to isolate the product for its further use [ 146].
It was heavy and made backing up cumbersome.
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