Second, to facilitate the otherwise cumbersome construction of targeting vectors, we adopted Gateway cloning system, which utilizes in vitro site-specific recombination by λ-phage-derived integrase complexes (BP and LR Clonases) [9].
Furthermore, the relative ease in performing specific knock-downs of proteins by siRNA in adult cardiomyocytes can in certain aspects be an alternative to the cumbersome construction of knock-out mice.
However, attributing the outcomes for young children to such an account would require the construction of a cumbersome developmental model, because adults did not so readily fuse spectral components when the principle of harmonicity was violated.
Some might think that with an appropriate SCFG (modeling a given class of objects) at hand, it is not really necessary to use an unranking method that implies cumbersome formalities such as admissible constructions and decomposable classes if we want to generate random objects of a fixed size n.
Nonetheless, materials and construction techniques remained so cumbersome that gas could not be used more than 160 km (100 miles) from a source of supply.
Mr. Davis and the Legislature have also put in place an aggressive program of energy conservation and taken steps to streamline California's cumbersome siting process to speed the construction of new power plants.
While novel, it is unclear how useful this approach will be since construction of transposon arrays is cumbersome, and it is clear that oncogenic cDNAs present in these arrays are not silent or inert so developmental defects resulting from ectopic expression of candidate oncogenes may occur.
Dresses, she said, owe at least some of their formidable staying power to their forgiving shapes, unfussy construction and obviation of caked-on accessories or cumbersome layering.
During construction, all project parties experience countless difficulties and cumbersome management problems.
Until now, sharing and executing new ideas across the architecture, engineering and construction (AEC) value chain have been hindered by cumbersome interoperability among the numerous software applications used during a project lifecycle.
Furthermore, the research design relied on a pen-and-paper survey and school-based administration, which made the construction of a between-subject design to be too cumbersome to effectively implement.
