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Exact(3)
This rather cumbersome computation gives the following result for the difference of the left- and right-hand sides of (25) expressed as U ∗ [ ( 1 + w ) ( ∑ ( α + j ) P j ) 2 + ( 3 α + 5 ) ( ∑ P j ) 2 ] − P ∗ ∑ ( α + j ) P j ∑ U j = ∑ j = 0 5 n − 2 Δ j α j (26).
In a computer simulation, sometimes simplifications or unrealistic assumptions have to be adopted in order to show the underlying mechanisms in a clear mode or even, as in this case, merely to avoid cumbersome computation.
The main purpose for that we set the presumed ribozyme-characteristic sequences no longer than 10 nt is to avoid cumbersome computation, based on the understanding that the key relation, i.e., the sequence-function correspondence of these ribozymes, is maintained in the simulation.
Similar(57)
(2) and (3), provided that the correct sequences of formations of the yielded elements can be identified without resorting to cumbersome computations.
Since the inversion of the covariance matrix in Equation 7 is very cumbersome and requires substantial computation and memory, further assumptions are needed to achieve a faster implementation.
As the analytical computations are cumbersome for the multi-antenna BSs, the channel power imbalance impact study in a more general case is made through simulation.
If Bayesian computation sounds too cumbersome, for the simplicity, follow Eddington's advice.
However, the piece-wise influence function can result in abnormal discontinuities in the resulting final movement and deformations at some points and the computation process is also cumbersome.
Certainly, increasing the length of the ribozymes and the self-cleaving label sites may bring our simulations more towards reality, but the system scale (represented, for example, by T NPPB ) would increase correspondingly, and computation would become more cumbersome, even unmanageable.
When the G-computation formula is too cumbersome to be evaluated analytically, the integration can be approximated through Monte Carlo simulation (47, 50) (see Appendix 2).
However, since the computation of FFRCT is a cumbersome process with limited availability, faster and less complex alternative CT-derived parameters have evolved, such as the decrease in corrected contrast opacification (CCO) across a stenosis and the transluminal attenuation gradient (TAG) along a coronary vessel [15 18].
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com