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Our historic needs for large kindreds to refine the relevant genetic interval and cumbersome analyses for positional cloning have limited the diseases amenable to study.
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These equations, however, do not require cumbersome FE analyses.
However, the enormous amount of data generated becomes cumbersome to analyse, and requires lots of dedicated time as well as expertise to manage [ 6].
Free text entry, for example, was very cumbersome to analyse for many of the fields, including primary risk fields e.g. smoking status, used in this research and consumed a significant amount of resource simply to recode already entered data.
However, the DE methods described above were developed for pairwise comparisons, creating cumbersome, and confusing analyses when processing data from more than two conditions.
For instance, given wood trait data from increment cores, a cumbersome process of repeated analyses on separate annual rings has been required to assess the stability of a QTL over time (Sewell et al. 2000, Brown et al. 2003, Ukrainetz et al. 2008).
Aluttis et al. (5) analyse the cumbersome path towards a coordinated European global health strategy from an agenda-setting perspective.
However, the estimation of complex item response models is more cumbersome than in confirmatory factor analyses models with continuous variables and often requires larger sample sizes.
Thermal models that are used to predict borehole heat exchange are characterized by either simplified formulations that are restrictive in their application, but utilitarian, or complex multi-dimensional analyses that are cumbersome to implement.
Mode-based analyses quickly become cumbersome and difficult to derive for multi-modal distributions.
Some of the ICU prognostic models require cumbersome data collection and employ complex statistical analyses to predict mortality.
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