Skin toxicity included dermatitis, erythematous diffuse or peripheral eruptions, pruritus, labial and peripheral oedema, culminating in grade 4 palmo-plantar erythrodysesthesia.
The most common precursors are pancreatic intraepithelial neoplasia (PanIN), which show a defined histological progression from the low-grade PanIN-1, through to the intermediate-grade PanIN-2, and culminating in the high-grade PanIN-3 (carcinoma in situ) [ 62].
Required to arrive at 8pm for the single 8.30pm service, we stood drinking unwanted cocktails while an exuberant purple-clad master of ceremonies called Pauly Paul submitted us to a welcoming salvo of weapons-grade zaniness, culminating in nipple-twiddling (his own) and a full-contact hug.
What's certain is that he has spent at least three hours on the Internet, because I saw it with my own eyes, last spring, when third grade culminated with an assignment to research rain-forest animals.
She may well be the post-time favorite, and deservedly so: she lost her first two races by a nose, and then reeled off three straight wins, all in graded stakes, culminating in a decisive 3 1/2-length win in the Grade 1 Santa Anita Oaks in early April.
Each year adds greater depth to the work the participants do, culminating during the students 11th grade year with discussions about college, career and the future.
CNAs identified mainly increased from the lowest to the highest grade of dysplasia, culminating with invasive OSCCs, which contained the largest number of changes.
Over the next 4 days (to day 10) progressive neurologic signs and high-grade fever developed, culminating in a generalized partial tonic-clonic seizure.
Owner: Exline-Border Racing, Gatto Racing, Zubok et al. Unusual for a New York-bred horse, Giant Expectations is based in California, where he's moved steadily up through the ranks, culminating in a win in the Grade 2 San Antonio at Santa Anita in December, his second graded stakes victory.
The three-year effort will train L.A. Unified teachers to help students at all grade levels learn about how computers work, culminating in advanced computer coding at the high school level.
The three-year effort will train L.A. Unified teachers to help students at all grade levels learn about how computers work, culminating in advanced computer coding at the high school level.
