The current market model's success has its base building from many culminating factors including interest rates, inflation, and commodity prices.
Platelets are deposited on damaged atherosclerotic plaques together with deposition of fibrin and thrombin and binding of a large protein called von Willebrand factor (vWf), collagen, and tissue factor, culminating in occlusive thrombus formation.
In contrast, loss of APC results in nuclear accumulation of β-catenin, which subsequently binds to Tcf-Lef (T cell factor/lymphoid enhancer factor) family of transcription factors, culminating in the activation of transcription and ultimately uncontrolled cell growth [ 41, 42].
There are three important factors culminating in a surge of millennial leadership.
The political unrest in East Pakistan and rivalry between the central government and the United Front-led provincial government was one of the main factors culminating in the 1958 military coup by Ayub Khan.
Mitochondrial integrity is compromised by I/R injury, often leading to opening of the mitochondrial permeability transition pore (MPTP) and release of pro-apoptotic factors culminating in cell death.
TAB/TAK/TRAF6 activity leads to IκBα phosphorylation and ubiquitination, culminating in nuclear factor-κB (NF-κB) activation and transcription of inflammatory genes [ 5].
It also has pro-inflammatory actions that lead to the up-regulation of chemokines, adhesion molecules and other fibrogenic growth factors, culminating in a decline in renal function.
Therefore, the joints of these participants may already be further along the pathological pathway of structural change from the normal joint to one with OA, where the factors culminating in a BML, and acting on the whole knee, are established.
Host cell recognition of micro-organisms or their products via PRMs is known to initiate pro-inflammatory signaling events that converge on the transcription factor, nuclear factor-κB (NF-κB), culminating in up-regulated cytokine/chemokine gene expression in cells.
Either a single factor or a great number of minor factors, all culminating at or near one date, determine the length of gestation.
