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This culminated in changes of SC morphology and functions.
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The mechanisms underlying the cell-death response involve protein kinases, which phosphorylate many substrates and culminate in changes in gene expression.
Signaling occurs through networks of proteins and nucleic acids, culminating in changes of gene expression and so changes in the proteome of the cell.
Accomplishing this goal begins with the improvement of software tools for data entry and use of the most rigorously complete and well defined data formats, and culminates in changes to the culture of data publication.
But after that promise ended in a last-place finish at the Games, USA Field Hockey returned home to figure out what went wrong, a six-month process that culminated in structural changes, the departure of the coach and the technical director, and the hiring of a new coach, Craig Parnham, in January.
It culminated in a change in the law.
Nine months of styling, singing and dancing lessons culminated in a single, Change Your Mind.
In the process, it's easy to neglect the underlying forces that improve life in small, hard-to-observe ways, culminating in important changes.
A discovery is not a simple act, but an extended, complex process, which culminates in paradigm changes.
This may culminate in neoplastic changes, especially adenocarcinoma of 'intestinal' type.
These events culminate in qualitative changes in the behavior of gene regulatory networks in which target genes are embedded.
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