However, an interaction of presentation order of the cueing condition with learning indicated that people who started the tasks with the non-cue version showed significantly better performance in the following cue condition, while participants who started with the cue condition stayed at the same performance level for both versions.
Thus, animals were trained in an entirely cued version of the MWM.
To carefully analyze the possible factors involved in the worse performance of Dyrk1A+/− in the MWM, a separate group of Dyrk1A+/− (n = 6) and wild type mice (n = 7) were tested in an entirely cued version.
Groups of 14 (single-cue version) and 16 (three-cue version) undergraduate students, 18 35 years of age, took part in the study for course credit.
On average, participants were correct on 79.84 % (SD = 13.14) of trials in the single-cue task, and on 84.67 % (SD = 11.09) in the three-cue version.
These assays revealed that the binding between Nhtt17Q and gp78 was retained by the proteins containing either the intact or cue-m version of the cue domain, but completely abolished in the cue-CD1/2 mutant that is also unable to bind polyubiquitin chains (Fig. 5B).
Of the two 1970 Top of the Pops performances, the "cue card" version appeared on The John Lennon Video Collection in October 1992, while the "knitting" performance was remixed and extended for release on the Lennon Legend DVD (2003).
In the cued-target version, the same pictures served sometimes as targets, sometimes as nontargets, with the current target defined by a cue at trial onset.
Cued-platform version: In this version, the platform is made visible to the mice by a small dark ball placed 12 cm on top of the platform, while the external cues are hidden by surrounding the pool with a black curtain.
Jill's responses, where present, have consisted of turns constructed of nouns or adjectives, and perhaps as a result of being put "on the spot," her dyspraxia has appeared much more prevalent than it was in Extract 2. David is able to assist Jill's participation by providing phonemic cues and versions of the required words for correct production because he knows the target words.
