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Unfortunately, despite the potential benefits afforded by the use of computational science, information science, biomedical informatics, and information technology derived methods and tools to support CTS, there are also numerous reports that demonstrate that achieving such benefits in CTS environment is extremely challenging.
As opposed to traditional investigator and domain specific approaches to driving biological, clinical, and translational problems, the modern academic CTS environment has experienced a major paradigm change that demands the increasing conduct of transdiciplinary and integrative basic, clinical, and translational research.
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An adapted Langendorff porcine heart model is feasible in a CT environment.
The aim of this study was to develop an explanted, perfused porcine heart model in a CT environment.
This study demonstrates the feasibility of ex vivo myocardial perfusion imaging and quantification in a CT environment at different grades of coronary stenosis.
In these examples from the urban CT environment, an immune response to Ascaris was between two- and three-fold more frequent in both adults and children than the presence of eggs in faeces.
Our results show that any learning-by-design CT-based environment needs to build in supports for programming, domain knowledge acquisition, and modeling tasks.
The "Literature review" section presents key design principles guiding the integration of CT and science education in CTSiM, and reviews known challenges and scaffolds for CT-based environments and learning-by-modeling environments for science.
AgentSheets (Repenning et al. 2010) is an example of one of the very few CT-based environments which include adaptive scaffolds.
The comparison of T f and the standard CT is made, as the measurement environment of the standard CT and our experimental environment is similar.
We conclude with a discussion of how our results have been influencing design of subsequent iterations of our system and the design of CT-based learning environments for teaching science in general.
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