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CTC, control type confidence, GPN, gene proximity network, TRN, transcriptional regulatory network.
To evaluate the extent of cell loss that occurs during loading of a DEPArray cartridge and sample injection into the main microchamber, counting experiments were performed using CellSearch CTC control samples (CellSearch CTC control kit, Veridex LLC), processed with the CellSearch CTC kit as an internal quality control for routine CellSearch CTC analysis in our lab.
In this study [ 9], digital control has been measured using the digital CTC (Control Type Confidence), a measure very similar to our metabolic coherence (see Methods), that evaluates the coherence of patterns of differentially expressed genes with the TRN.
In order to estimate the realistic extent of cell loss during this entire sample loading step, we first performed counting experiments using CellSearch CTC control samples processed with the CellSearch CTC kit.
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CTC denotes the control complexity.
It was achieved by creating diagnostic intrusive actions (DIA), also known as an active diagnosis, which separate component detection from normal coordinated torque control (CTC) action, which otherwise would influence the component outputs.
It is equipped with centralized traffic control (CTC), has eight bridges, two tunnels and no level crossings.
CTs included purified water as a control (CTC) and two experimental groups that used either a 1 5 dilution of citric acid denture cleanser (CT5) or a 1 8 dilution of citric acid denture cleanser (CT8).
C. albicans biofilms were developed for 72 h on PMMA resin specimens (n = 168) and then randomly assigned to 1 of 3 cleansing treatments (CTs): purified water, used as a control (CTC); 1 5 dilution of citric acid denture cleanser (CT5); or 1 8 dilution of citric acid denture cleanser (CT8).
Additionally, although this study included a high-risk population (at least four positive nodes), neither the experimental (HD-CTC) nor the control (taxane-devoid chemotherapy) regimens are considered standard for node-positive breast cancer in this era.
The negative likelihood ratio (LR-) was defined as percent bladder and urothelial cancer patients with CTC-negative results (CTC-) divided by that of control subjects who were CTC-.
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