Exact(1)
We have produced an Fc conjugate of colony-stimulating factor (CSF) 1 with an improved circulating half-life.
Similar(59)
ChP performs many functions, including production of CSF [1] [3].
Diluted patient sera (1 100) or CSF (1 10) were added to the plates.
The validation cohort was separated into CSF-1-low CSF-1-low CSF-1-lowhigh patients with the sand cutoff value.
To investigate the expression and regulation of colony-stimulating factor 1 (CSF-1) and its receptor, C-FMS, in endometriosis.
Objective: To evaluate the regulation and expression of CSF-1 and its receptor c-fms in endometrial cells.
To investigate the role(s) of colony-stimulating factor 1 (CSF-1) on the development of early endometriosis in a murine model by comparing rate of lesion formation in mice [1] homozygous for a CSF-1 mutation versus syngeneic controls and [2] after treatment with imatinib, a commercially available tyrosine kinase inhibitor that alters interaction(s) between CSF-1 and its receptor, c-fms.
What regulates CSF-1 release by tumor cells?
The CSF-1 pathway is required for macrophage differentiation and survival, yet previous work suggests the CSF-1 pathway may also drive tumor cell progression.
Osteopetrotic csf-1op/op mice are homozygous for an inactivating mutation in the csf-1 gene, and hence lack the CSF-1 protein [26].
However, a radioimmuno-assay of lung tissue CSF-1 revealed a reduced CSF-1 expression in the heterozygote (data not shown).
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