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If the current experiments will be performed on a low clonogenic CSC (i.e. low CSC faction) the authors will need to extend their titration curves.
CSC is used to describe intra-flow interference, which is defined as CSC i = w 1 if CH ( prev ( i ) ) ≠ CH ( i ) w 2 if CH ( prev ( i ) ) = CH ( i ) (2).
Path weight of the metric is defined as follows: ILA p = α × ∑ link i ∈ p MTI i + ∑ node i ∈ p CSC i (27).
where CSC i indicates the channel reserved for node i ' s transmission and prev(i) denotes the previous hop of the node i through the route p. Thus CSC can capture the inference only between two successive links.
Metric of interference and channel switching is based on ETT and is explained as follows: MIC p = 1 N × min ( ETT ) ∑ link l ∈ p IRU l + ∑ i ∈ p CSC i (10).
The MIC value for path p is defined as MIC ( p ) = α ∑ link l ∈ p IRU l + ∑ node i ∈ p CSC i (3) α = 1 N × min ETT (4).
Similar(50)
Since the higher order CSCs (i.e., C S C 5 is the highest order and C S C 1 is the lowest order CSC) have only a subset of the assets owned by the lower order CSCs, their adjusted impact values are predictably lower.
As recently reviewed [4], there have been two main approaches to isolate CSCs, i.e., candidate versus operational approaches.
Both chemoresistant cell lines also demonstrated functional characteristics of CSCs (i.e., sphere formation and growth in soft agar).
The ability of the tumor to generate its own vasculature in the ectopic environment implied a conditional existence of CSCs, i.e. evident in one in vivo environment but not in the other (and not in vitro).
Brabletz et al. proposed the existence of two CSC populations: (i) stationary CSC subpopulation and (ii) migratory CSC subpopulation.
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