Fluid Crystallization, Self-Assembly Lab, MIT, Arthur Olson, Autodesk Inc., International Design Center, MIT.
A typical of the lab projects, namely crystallization of magnesium ammonium phosphate hexahydrate (MgNH4PO4·6H2O), commonly known as struvite, is presented in this paper, of which the experimental results agreed with most published literature.
It was all very subjective, of course Owsley would pay attention to the music they were playing in the lab at the point of crystallization, and would then pray over the equipment to imbue it with positive vibes.
The temperature for protein crystallization screens is usually chosen arbitrarily in most labs.
The crystallization of proteins is going to remain primarily a lab-scale process; however, new pharmaceuticals based on proteins are entering the marketplace and will ultimately require scaling up to large batch operations.
Crystallization was carried out as one of the undergraduate chemical engineering lab projects.
In this study, crystallization process simulation combined with experimental model parameter determination at lab-scale is investigated in order to allow the integration of crystallization unit operation into conceptual process design for the purification of complex mixtures and possibly assist in formulation.
It is the first time a simulated model of protein crystallization has matched well with the temperature, salinity and other crystal-forming conditions structural biologists observe in the lab.
The new lab-scale equipment allows for isolation and manipulation of individual crystallization tasks.
The findings are anticipated to have implications for a number fields ranging from fluid dynamics, lab-on-a-chip devices, chemical engineering, nanomaterials synthesis, protein crystallization to advanced drug delivery as well as chip fabrication.
