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Furthermore, 50% of patients achieved at least a 50% increment in headache free days twice that of the baseline in a 30-day period, and 31% achieved at least a 75% increment in crystal clear days three times the baseline in a 30-day period.
A responder was defined as 50% reduction in headache or migraine days, or an increment in crystal clear days twice that of the baseline in a 30-day period.
Khalil and coworkers, for example, define as a responder any patient with either a 50% reduction in headache or migraine days or an increment in crystal clear days twice that of the baseline in a 30-day period (Hull criteria) [25].
An increment in crystal clear days twice that of baseline.
There were 1,131 crystal clear days pre- OnabotulinumtoxinA treatment and 2,502 post- OnabotulinumtoxinA treatments.
The 50% or 75% reduction data (and ≥2 and ≥3-fold increase in crystal clear days) are summarised in Table 2.
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So, a couple of weeks ago, on one of those crystal-clear days that made me think I was in another waterfront city (Baltimore Chicago Bostonon?), I went downtown to check it out.
Figure 4 Change in crystal-clear days pre- and post-BOTOX in chronic migraine sufferers.
He was driving to the grocery store in Montclair on a crystal-clear day from his home in Roseland, where he lived, and kept getting "magnificent glimpses" of Manhattan from the tops of hilly streets on what is known as First Mountain.
Data were collected for the number of headache, migraine and crystal clear (headache free) days.
That became crystal clear a few days ago when the Los Angeles chapter of the 100-year-old civil rights organization put its collective credibility in jeopardy in a campaign against... a Hallmark card.
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