Sentence examples for crucial trigger for from inspiring English sources

Since the seminal experiments of Ringer on cardiac muscle contraction [32], it has been recognized that Ca2+ entry into cells provides a crucial trigger for life and death processes.

Overall, the division employed and led a clear and simple approach to the implementation of the program in each practice and this was seen as a crucial trigger for change.

Even though there is an equal possibility for genes that are deleterious to be switched on through changes in the enzymes that alter the epigenome, it would seem that the switching off of genes is the crucial trigger for the progression of tumours through altering the inherent stable balance in cells.

These results indicate that Ca2+ ions in the postsynaptic neurons are crucial triggers for CP-AMPAR-dependent LTP, similar to their role in traditional NMDAR-dependent forms of plasticity (Figure 4C; control = 236±20.8%; BAPTA = 95±9.5%; P<0.001).

Hypoxia and HIF, major contributors to the pathogenesis of PH, have been thought to act as crucial triggers for miRNA dysregulation in PH.

Although we did not narrow down the toxic fragment substantially, our data have provided proof-of-principle evidence that the exon-fusion approach has promising potential for further defining the toxic SOD1 fragment that is crucial for triggering ALS and thus as a molecular target for designing rational therapy.

High intracellular Ca2+ levels are crucial for triggering muscle contraction, whereas low levels are critical for initiating muscle relaxation.

The genius inventor may have been onto something: Scientists have since found mind wandering to be crucial for triggering insights.

For a more complete understanding of the STR in a quiescent neuron, in the context of noise-induced irregular and incoherent spiking, it is necessary to determine which features of the input signal are crucial for triggering spikes with precise timing.

Interestingly, our recent study showed that BDNF expression in the retina is increased by EE in developing animals and these higher levels of BDNF are crucial for triggering retinal functional development [8].

Thus, the binding of the side chain of L-arginine via interaction with both domains of the protein is likely crucial for triggering conformational change required to generate the bindings sites of the other substrates.