These contextual elements are crucial to infer and adjust learning content that is compatible, in terms of size, media-type, and security with the technological set-up that characterizes the surrounding environment.
The establishment of correct orthology and paralogy is crucial to infer accurate evolutionary relationships.
The knowledge of the dynamical properties of different fundamental regulatory circuits is crucial to infer the selective pressures that the cell has suffered during its evolution.
The phylogeny with gyrB [19] and 32 kDa protein genes [20], which are crucial to infer evolutionary relationship in closely related species also confirmed the above findings (Figure S1).
This limitation will likely apply to other operational proteins candidates to be used as markers for the reconstruction of global eukaryotic phylogenies but, as already discussed, their inclusion in multi-marker analyses becomes crucial to infer several deep nodes that the traditional supermatrices of informational proteins have failed to resolve.
This information, combined with data on prey spectra and distributional ranges, will be crucial to infer under which conditions the army ant life-style evolved, which general factors promoted the subsequent niche shifts in different lineages, and where these transitions took place.
It is thus of crucial interest to infer contacts or build contact proxies from data with lower spatial resolution data or coming from other sources.
Another crucial factor to infer from temporal data is gene flow.
Indeed, as demonstrated in our analysis of MYC dataset (FILTER and NOFILTER experiments), removal of filtering steps when executing POTION can increase positive selection detection to values much higher than the ones observed in other GSPSD, strongly suggesting filtering steps to be a crucial procedure to infer reliable positive selection.
The choice of a specific calibration date is therefore potentially crucial to accurately infer molecular dates (e.g., [ 6]).
