Exact(3)
In recent times, Bruton's tyrosine kinase (BTK), a crucial terminal kinase enzyme in the B-cell antigen receptor signalling pathway has emerged as a novel target [ 102].
12 14 Biomechanical and kinematic studies have demonstrated that the BF is subject to the highest levels of muscle tendon unit stretch throughout the crucial terminal swing phase in (high speed) running.
Owing to the smaller fascicular length of the BF muscle, compared to the ST, 45 it is less stretch tolerant and less suited to contribute to energy storage through negative work and to control the hip and knee torques in its distal range of motion in this crucial terminal phase of running.
Similar(57)
Although she officially first appears in Resident Evil 2, eagle-eyed players will notice that Ada is mentioned in the Researcher's Letter file in the original game and her name is the password to a crucial computer terminal.
Prolactin hormone activity is crucial for terminal differentiation, which leads to normal milk-producing alveolar units during pregnancy and lactation.
Epidermal Differentiation Complex (EDC) is a family of S100 related genes crucial for terminal differentiation of human epidermis [ 55].
Analysis of different KCNQ2 and KCNQ3 chimeras and deletion mutants combined with in-vitro binding analysis pinpointed a crucial C-terminal syntaxin 1A-association domain in KCNQ2.
However, although our bait (FLAG AF4-1) lacks the crucial C-terminal-binding domain, we were able to identify various known and new molecular partners, thereby providing further insight into AF4 function in normal and leukaemic conditions.
There are significant sequence differences between the rat and human TIMP-1 most notably in the crucial N-terminal region, human is CTCVPPH and rat is CSCAPTH, which has large effects on specificity and might reflect differences in targets between the two species.
The latter is crucial for the terminal differentiation of OPCs since ablation of SOX10 would lead to an altered migration pattern and reduced quantity of OPCs due to enhanced apoptosis [ 142].
It has also been observed that the C-terminal amino acid residues, which are known to be crucial for N-terminal glycosylation function [ 24], are conserved in DAD1 from a wide range of organisms.
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