Sentence examples for crucial mutation from inspiring English sources

Ram Sasisekharan, a Massachusetts Institute of Technology researcher on a team that did a 2009 study that made a bird flu more transmissible in ferrets, said another crucial mutation was in the HA gene, which codes for the hemagglutinin spike that attaches the virus to cells.

The fact that all of these possible Syndrome X cases are girls is intriguing – it could mean that the crucial mutation is on their X chromosome.

Iommi's lack of fingertips led to other crucial mutations in his guitar playing – namely the use of thinner, detuned strings.

A full-scale, double-blind trial is now under way.A similar approach of identifying one of the crucial mutations that has led to a cancer arising, and attacking it is behind Dr Bang's lung-cancer treatment.

That means crucial mutations are more likely to happen, but also that in any given cancer there is a lot of mutational "noise".Until now, this has made it more difficult to discover which mutations are important and which merely incidental.

Normal mutation rates are thus quite sufficient to explain the crucial mutations needed to drive tumorigenesis, but how many mutations exist within a typical cancer?

Recently, some of the crucial mutations have already been confirmed to directly contribute to the tumorigenesis of pancreatic cancer, indicating the underlying relationship between mutations of candidate genes and the process of tumorigenesis [ 127].

The lack of stability of adaptive variants is evidenced by the instability of the crucial PB2 E627K mutation, implicated in replication in humans [35] and high virulence of human H5N1 infections [36].

Thus, the concentration of drugs in subculture plates is crucial to mutation frequency assays.

This general-level point is as simple as it is crucial: if mutation is nonrandom, then selection on interactions has a hereditary effect.

Knowledge of the interactions may provide insights into the mechanisms of crucial 'driver' mutations in oncogenesis.