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The functional stability and homogeneity of these states is crucial for the function of larger organs and for the overall survival of the organism.
Therefore, under the hypothesis that there is an underlying dynamics (i.e., fluctuation profile) for the three-dimensional (3-D) structure of a protein, which is crucial for the function, our metric dfi quantifies the contribution of each position to this functional dynamics and is designed to capture the key residues mediating the function through the residue interaction dynamics.
Mechanical flexibility is crucial for the function of proteins.
These results, together with its expression in brain tissues, suggest that miR-130a may play an important role in regulating expression of genes crucial for the function of the nervous system.
This structural flexibility is crucial for the function and regulation of these enzymes and identifying compounds that can interfere with it represents an attractive approach for developing novel modulators and drugs.
Specific interactions between the receptor and ligand are crucial for the function and activation of this receptor, as implied by the single point mutation, H305Q, causing symptoms of Type II Rickets.
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Those companies provide services "crucial for the functioning of the Internet" so consumers can gain access to "Internet content with the necessary quality," it said.
And she observed that no single expertise can substitute for this kind of dispersed contextual knowledge that is crucial for the functioning of complex urban systems.9.9
Methods for "cleaning up" (or recognizing) states of a neural network are crucial for the functioning of many neural cognitive models.
In the majority of inhibitors reviewed in this article, the phosphorus plays the role of zinc bonding, as most MMP inhibitors are designed to do, since the catalytic zinc ion is crucial for the functioning of these enzymes.
Surprisingly, deletion of the UBL domain does not significantly alter the degradation of CPY* or RTA (Figure 2C, 3C), suggesting that the UBL motif is not crucial for the functioning of Usa1 in proteolysis.
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