Sentence examples for crucial for functionality from inspiring English sources
In summary, this study represents a novel method of displaying eukaryotic proteins on bacterial carriers such as L. lactis when post-translational glycosylation is crucial for functionality.
As the cytosolic loop between the N-terminal TMD0 and the core transporter is crucial for functionality in some ABC transporters, we assigned the domain boundary between the core ABCB6 and TMD0 to residue 205, which is immediately proximal to the predicted five transmembrane helix bundle of TMD0.
As the cytosolic loop between the extra N-terminal domain and the core ABC complex was shown to be crucial for functionality in other ABC transporters [ 7, 31], the ABCB6 core was designed to include the entire cytoplasmic loop connecting the fifth and the sixth transmembrane helices.
P. pastoris also produces disulfide-bonded and glycosylated proteins, which are crucial features for functionality [ 13].
Obviously, the seed sequence is crucial for miRNA functionality, but other regions, such as those next to the seed, have also recently been involved in miRNA functionality [ 9].
Although GmSKRPs do not contain any known domains, we found that the lysine and arginine residues are crucial for protein functionality.
Conserved residues, localization of autotransport-deficient mutants, and analysis of surface properties in our study provide data that conservation of structural elements, rather than surface characteristics per se, is crucial for autotransport functionality in this region.
The modulatory feedback connections, that exist between different model components and allow the transfer of information via a "soft gating" mechanism, are crucial for the functionality of the model.
The biophysical properties of biological membranes are crucial for the functionality of membranous organelles, including the mitochondria and ER.
In addition to being crucial for the functionality of many individual proteins, intrinsic disorder plays a vital role in the control of almost all cellular processes.
