Sentence examples for crucial defects from inspiring English sources

Actually, decreased activities of NADH-cytochrome c reductase are observed even in 4-week-old SAMP8 mice, suggesting crucial defects in maintenance of the respiratory chain [ 63].

This system may be suitable for the study of other neurodevelopmental and neuropsychiatric syndromes in which there are moderate but crucial defects in cortical organization and function.

In the past, the Court saw politics through the lens of pluralist theory, the crucial defect of which was the risk that minorities would be politically marginalized.

These findings led us to the hypothesis that an unanticipated crucial defect resulting from the elimination of IL2 might be a lack of a negative regulatory feedback function [7].

With the continuous presence of insulin resistance, progressive loss of β-cell function is the crucial defect.

The earlier the gonadal development program is interrupted by a crucial defect, the less the gonad is able to differentiate into either a testis or ovary.

However, this method cannot simulate the chemical reaction dynamics at reaction temperatures, which is crucial fault and defect for more precise and accurate design to establish next-generation nanotechnology.

These have been well known for years to be crucial gene defects in many common tumors.

Voids are crucial point defects that are inevitable during fabrication and deformation of materials.

Cracks are the main source of failure in the production of metal parts: systems for checking their presence are therefore crucial for defect-free production.

Therefore, because Chd1l responds to DNA damage through its interaction with PAR, and because DNA repair is crucial during embryogenesis, defects in DNA repair could underlie the Chd1l early embryonic arrest.