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As the CrT is located on the X-chromosome [2], mutations in the CrT show X-linked inheritance [3], [4].
Males carrying deletions in the CrT show moderate to severe intellectual disability with significant speech delay or lack of speech [3] [11].
Patients in whom there has been a significant response of EMVI to CRT show improved DFS.
While most patients with CRT show very little fluctuation in LV thresholds, there are individuals who show marked fluctuations, especially those patients with higher (>2.0 V) capture thresholds.
In summary, studies of oxaliplatin based CRT show promising activity with acceptable toxicity, may be potentially safer than cisplatin-based regimen, and therefore justify formal testing in a pre-operative study.
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Fischer et al. reported that changes in the flow-metabolic phenotype (blood flow × maximum standardized uptake values (SUV)) of RC after CRT showed high accuracy for the prediction of histopathological response to CRTP (AUC 0.955, 95%% confidence interval 0.833-1.000) using a cut-off value of −75%% [101].
Conversely, Arabidopsis plants over-expressing a maize CRT showed reduced leaf chlorosis when grown on Ca2+-depleted media compared to wild-type control plants [9].
Univariate analysis of survival after subsequent CRT showed a non-significant trend towards better results when CRT was combined with S-1 (Table 6).
In the present study, histological effect of CRT showed that the incidence of grade IIb or more was 45.8% in PD and 18.8% in PD-SAR.
Although the mean number of injections during 1-year period varied in different studies, namely, 2.3 and 3.8, BCVA and CRT showed comparable results in all studies.
In these studies, the application of DW imaging to evaluate the early response of the primary rectal carcinoma to CRT showed conflicting results on considering the correlation of the diffusion values and tumor response.
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