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Now, however, CRP testing seems ready to catch on for several reasons.
Dr. Nabel said national panels were likely to revise their official guidelines for doctors to recommend CRP testing and statin therapy for some people not previously considered candidates.
That first round of JUPITER results made a big splash, but it left room for debate about how CRP testing and lowering should fit into cardiovascular care.
Even if heart attacks were caused by inflammation, CRP testing wouldn't be useful unless it's proved to be a good predictor.
So, CRP testing can be very useful in people with normal cholesterol levels who still may be at risk for cardiovascular disease.
Until now, many doctors have been reluctant to recommend CRP testing as part of routine care because they believed the results wouldn't have an effect on treatment choices.
Because atherosclerosis is fundamentally an inflammatory process, many experts believe that CRP testing could lead to early detection and therefore save lives.
However, new drug therapies that specifically target cardiovascular inflammation will open the door to wider use of CRP testing, Dr. Libby predicts.
The experts, however, do not recommend CRP testing either for those at otherwise low risk of heart disease or for those known to be at high risk -- those who already have signs of trouble, since they should already be getting aggressive treatment.
Prior studies evaluating the use of CRP in the acute setting vary with the risk of disease, length of follow-up, and type of CRP testing utilized.
Similar(1)
We compared: 1) hs-CRP testing followed by rosuvastatin treatment for patients with hs-CRP levels >/=2.0 mg/l; and 2) usual care (i.e., no testing and no treatment).
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